Identifying & Selecting Specific Cell Lines to Optimize AAV Transduction Efficiency & Increase AAV Potency Assay Sensitivity
Time: 11:30 am
day: Day Two AM- Track A
Details:
• Mechanisms for Screening Cell Lines: Exploring strategies to screen cell lines based on therapeutic area relevance to improve assay sensitivity
• Cell Line Optimization Towards AAV: Discussing methodologies for optimizing cell lines to enhance AAV transduction efficiency
• Comparing the use of stable versus transfected cell lines to minimizing batch-to-batch variability in potency assessment for rare disease
• Reducing the multiplicity of infections in cell-based bioassays to increase assay resolution and minimize cellular toxicity