Damon Barbacci

Company: Genentech

Job title: Director - Analytical Development

Seminars:

Decoding AAV Degradation: Building a Framework for Stability-Indicating Assays 2:30 pm

Explore degradation pathways under different storage conditions (frozen, refrigerated, room temperature) Investigate how titer loss correlates with capsid integrity and genome degradation Define criteria for selecting effective stability-indicating assays and extending retest datesRead more

day: Conference Day Two - Physiochemical

Advanced Stability Testing: Implementing Stress & Accelerated Stability Conditions for Commercial Readiness 9:00 am

Establishing robust stability profiles is essential yet challenging due to the limited understanding of degradation pathways and assay limitations. This session will focus on designing effective stress and accelerated stability studies, interpreting degradation data to support shelf-life and retest justifications, and navigating evolving regulatory expectations. Attendees will explore best practices for building confidence in product…Read more

day: Pre-Conference Day Track B AM